Article: Derks et al, 2022
- Peer reviewed article: Derks, J., Leduc, A., Wallmann, G. et al. Increasing the throughput of sensitive proteomics by plexDIA. Nat Biotechnol (2022). 10.1038/s41587-022-01389-w , Nature Research Briefing
- Replication of the analysis: C Vanderaa \& L Gatto
Single-cell proteomics method: plexDIA
Sample preparation method: nPOP
plexDIA Data plexDIA @ massIVE plexDIA code
plexDIA data organized by experiments
All RAW and processed data from the plexDIA article are organized in this directory. Below are links to processed data from single cells, cells isolated based in DNA content (cell cycle phases) and from LFQ-bench style benchmarking experiments.
Processed single-cell data
Proteins x single cells data matrix
Processed cell division cycle data
Processed benchmarking data
plexDIA RAW data and search results from DIA-NN
The repositories below contain RAW mass-spectrometry data files generated by a first-generation Q-exactive instrument as well as the search results from analyzing the RAW files by DIA-NN. Searching plexDIA data with DIA-NN is described in this tutorial.
- MassIVE Repository for version 1 (Bulk plexDIA data):
- MassIVE Repository for version 2 (Bulk and single-cell plexDIA data):