Single Cell Proteomics
Methods & Data
Quantifying proteins in single cells with mass spectrometry
Perspectives Reviews Highlights
Each cell performs its biological functions by changing the abundance, localization, modifications and interactions of its proteins. Analyzing these processes requires quantifying proteins in single cells, which is the focus of this web portal. Its pages include both single-cell proteomics methods and data from single mammalian cells, both primary cells and cell lines.
Methods Data Sample prep Computation Biology
Perspectives
- Framework for multiplicative scaling of single-cell proteomics, Nature Biotechnology
- Learning from natural variation across the proteomes of single cells, PLOS Biology
- Driving Single Cell Proteomics Forward with Innovation, Journal of Proteome Research
- Unpicking the proteome in single cells, Science
- Transformative Opportunities for Single-Cell Proteomics, Journal of Proteome Research
Reviews
- Single-cell protein analysis by mass spectrometry, Current Opinion in Chemical Biology
- Single cell protein analysis for systems biology, Essays in biochemistry
- Scaling up single-cell proteomics, Molecular and Cellular Proteomics
Highlights
- Highlight by C&EN
- Highlight by Nature
- Highlight by Nature Methods
- Technology feature at Nature Methods
- Single-cell proteomics for the Human Cell Atlas
About
This site provides resources and data for single-cell proteomics from the Slavov Laboratory
The research reported here has been supported by funding from the NIH Director’s Award by an Allen Distinguished Investigator Award from the Paul G. Allen Frontiers Group and by CZI.